Immunohematology
blood typing
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Pathophysiology. Immunohematology
Blood types rHfactor compatible wit....
A Anti-B o
·
rHnegative blood types can only receive
o antibodies
] ∴
□
A+
/A.
negative blood types .
‰
·
rH positive can receive BOTH positive
·Anti-A
antibodies_
… B +/ B -
AND negativ blood types.
ABabodies AB +/AB- ∞
·
Agglutinogens :
Antigens. Markers on
CB a O erythrocytes
·
Agglutinins: Antibodies. . Foundinplasma
y
'dB '
antibodies ·
Agglutination : clumping of RBCs dueto
o +f0 -
antibody/antigen reaction.
Erythroblastosis fetalis
Mother's bod (antibodies) attack baby's RBCs.
·
rH negative mother carries an rH-positive baby (from father)
Mother's body produces antibodies as the baby's blood mixes with her's a sees itas an enemy . -
usu occurs during first pregnancy/delivery
·
First baby is usu fine. Next rH-positive baby is impacted
·
Antibodies produced now crosses the placenta & destroysthe baby's RBCs (hemolysis) ·
Baby's symptoms :
-
Anemia fromhemolysis
-
Jaundice from bilirubin buildup
-
Enlargementof liver andspleen.
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